{"id":3251,"date":"2023-10-29T09:49:41","date_gmt":"2023-10-29T09:49:41","guid":{"rendered":"https:\/\/www.epidemiologie.nl\/cursus\/molecular-and-genetic-epidemiology\/"},"modified":"2024-07-04T15:41:51","modified_gmt":"2024-07-04T15:41:51","slug":"molecular-and-genetic-epidemiology","status":"publish","type":"cursus","link":"https:\/\/www.epidemiologie.nl\/en\/cursus\/molecular-and-genetic-epidemiology\/","title":{"rendered":"Molecular and Genetic Epidemiology"},"content":{"rendered":"<p>Topics covered: biomarkers, study designs in molecular epidemiology, genetic epidemiology, mendelian randomization, big data \/ omics<\/p>\n<p>Biomarker profiles that can be used in molecular epidemiology can range from just a few targeted markers to a whole metabolome, and may include the measurement of (epi)genetic variation, gene expression, proteins, small molecules, and functional assays. Epidemiology has been proven valuable to identify associations between exposure and disease, in particular because it enables us to study long-term effects of \u2018normal\u2019 variation in exposure in populations. However, traditional epidemiology does so without obtaining information of the biological processes that underlie these associations. Molecular and genetic epidemiology have the power to open up this \u2018black box\u2019. It will not only enhance the measurement of exposure, effect, and susceptibility, it will also give insight in complex biological mechanisms, and generate novel hypotheses about disease mechanisms. In this module, students will be familiarized with the different types of molecular biomarkers that can be used in epidemiological studies, including those measured with novel high-throughput \u2013omics technologies. They will learn the pros and cons of different study designs used in molecular and genetic epidemiology, including Mendelian randomization.<\/p>\n<p>Assessment: attendance and active participation, written exam<\/p>\n","protected":false},"template":"","class_list":["post-3251","cursus","type-cursus","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Molecular and Genetic Epidemiology - Vereniging voor Epidemiologie<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.epidemiologie.nl\/en\/cursus\/molecular-and-genetic-epidemiology\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Molecular and Genetic Epidemiology - Vereniging voor Epidemiologie\" \/>\n<meta property=\"og:description\" content=\"Topics covered: biomarkers, study designs in molecular epidemiology, genetic epidemiology, mendelian randomization, big data \/ omics Biomarker profiles that can be used in molecular epidemiology can range from just a few targeted markers to a whole metabolome, and may include the measurement of (epi)genetic variation, gene expression, proteins, small molecules, and functional assays. Epidemiology has [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.epidemiologie.nl\/en\/cursus\/molecular-and-genetic-epidemiology\/\" \/>\n<meta property=\"og:site_name\" content=\"Vereniging voor Epidemiologie\" \/>\n<meta property=\"article:modified_time\" content=\"2024-07-04T15:41:51+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/cursus\\\/molecular-and-genetic-epidemiology\\\/\",\"url\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/cursus\\\/molecular-and-genetic-epidemiology\\\/\",\"name\":\"Molecular and Genetic Epidemiology - Vereniging voor Epidemiologie\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/#website\"},\"datePublished\":\"2023-10-29T09:49:41+00:00\",\"dateModified\":\"2024-07-04T15:41:51+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/cursus\\\/molecular-and-genetic-epidemiology\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/cursus\\\/molecular-and-genetic-epidemiology\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/cursus\\\/molecular-and-genetic-epidemiology\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cursussen\",\"item\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/cursussen\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Molecular and Genetic Epidemiology\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/#website\",\"url\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/\",\"name\":\"Vereniging voor Epidemiologie\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.epidemiologie.nl\\\/en\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Molecular and Genetic Epidemiology - Vereniging voor Epidemiologie","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.epidemiologie.nl\/en\/cursus\/molecular-and-genetic-epidemiology\/","og_locale":"en_US","og_type":"article","og_title":"Molecular and Genetic Epidemiology - Vereniging voor Epidemiologie","og_description":"Topics covered: biomarkers, study designs in molecular epidemiology, genetic epidemiology, mendelian randomization, big data \/ omics Biomarker profiles that can be used in molecular epidemiology can range from just a few targeted markers to a whole metabolome, and may include the measurement of (epi)genetic variation, gene expression, proteins, small molecules, and functional assays. 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