More than one billion people worldwide are living with a mental or addictive disorder, making them both leading causes of disability and a significant risk factor for premature mortality (Arias et al. (2022) eClinicalMedicine). Treatment of mental disorders usually involves drug therapy, psychotherapy, or a combination of both. Psychopharmacology, the topic of this course, is the scientific study of the effects drugs have on mood, sensation, thinking, and behavior. In this crash course on psychopharmacology, we will look at drug treatment for psychiatric disorders such as depression, anxiety and ADHD. How do these (psychoactive) drugs work? How and why do they invariably lead to side-effects? And how do these side-effect affect adherence?
To answer these questions, we should strive to become a ‘neurobiologically empowered psychopharmacologist’, according to the renowned psychopharmacologist Dr. Stephen Stahl. In this course we therefore aim to give you at least a basic understanding of the underlying neurobiology of anxiety, depression, ADHD, addiction and cognition.
As a final topic, to explain how the most effective drug dose for one person can be either ineffective or dangerous for somebody else, we will also cover both pharmacokinetics (how our bodies interact with the drugs we take) and pharmacogenetics, the study of the effect of genomic variations on drug response.
