Cursussen

This course provides insight in the basic terminology and principles used in epidemiology. The course starts with the history and design of epidemiological research, and the different measures of frequency and association. Also, the principles of bias and confounding are addressed.

In medicine and health sciences we often measure constructs that are not directly observable, such as quality of life, pain, or depression. Measurement of such constructs requires use of questionnaires, which validity and reliability is assessed using statistical measurement models. The Item Response Theory (IRT) provides statistical models which model the relationship between the construct and…

Clinimetrics is the scientific discipline that aims to (1) develop methods of assessing the properties of health measurement instruments, (2) apply those methods to develop new, or evaluate existing, health measurement instruments, with the aim (3) to improve the quality of measurements. The choice of an appropriate measurement instrument is a key issue in all scientific research. Measurement i…

Systematic reviews of diagnostic accuracy evaluate and synthesize the totality of evidence about the accuracy of a single diagnostic test, or the difference in accuracy of multiple tests. Reviews of diagnostic accuracy studies are usually more challenging to perform than those of intervention studies. In this course, we will discuss and practice the methods relevant for each step of the review…